Mystery pumpkins for Halloween

10 Poisons Used To Save Lives

In this list we look at a variety of substances (poisons and venoms) that are normally things we would avoid as they can kill or badly damage us, but are found in the medicine bottles and pill boxes of doctors and pharmacists around the world.

10 Warfarin

Warfarin is an anticoagulant. It was initially marketed as a pesticide against rats and mice and is still popular for this purpose, although more potent poisons such as brodifacoum have since been developed. A few years after its introduction, warfarin was found to be effective and relatively safe for preventing thrombosis and embolism (abnormal formation and migration of blood clots) in many disorders. It was approved for use as a medication in the early 1950s and has remained popular ever since; warfarin is the most widely prescribed anticoagulant drug in North America. Despite its effectiveness, treatment with warfarin has several shortcomings. Many commonly used medications interact with warfarin, as do some foods, and its activity has to be monitored by frequent blood testing.

9 Cone Snail Venom

Cone snails are medium-sized to large, sophisticated predatory sea snails. These snails hunt and immobilize prey using a modified radular tooth along with a poison gland containing neurotoxins; this is launched out of its mouth in a harpoon-like action. Live cone snails should be handled with care or not handled at all, as they are capable of "stinging" humans with unpleasant results. The sting of small cones is no worse than a bee sting, but the sting of a few of the larger species of tropical cone snails can be serious or even fatal to human beings. The venom of some cone snails, such as the Magician cone, Conus magus, shows much promise for providing a non-addictive pain reliever 1000 times as powerful as, and possibly a replacement for, morphine. The first painkiller Ziconotide derived from cone snail toxins was approved by the U.S. Food and Drug Administration in December 2004 under the name "Prialt". Other drugs are in clinical and preclinical trials, such as compounds of the toxin that may be used in the treatment of Alzheimer's disease, Parkinson's disease, and epilepsy.

8 Wolfsbane
The roots of Aconitum ferox (Wolfsbane) supply the Nepalese poison called bikh, bish, or nabee. It contains large quantities of the alkaloid pseudaconitine, which is a deadly poison. Aconitum palmatum yields another of the bikh poisons. The root of Aconitum luridum, of the Himalaya, is said to be as virulent as that of A. ferox or A. napellus. In Western medicine preparations of aconite were used until just after the middle of the 20th century, but it is no longer employed as it has been replaced by safer and more effective drugs and treatments. Internal uses were also pursued, to slow the pulse, as a sedative in pericarditis and heart palpitations, and well diluted as a mild diaphoretic, or to reduce feverishness in treatment of colds, pneumonia, quinsy, laryngitis, croup, and asthma due to exposure. Taken internally, aconite acts very notably on the circulation, the respiration, and the nervous system. The pulse is slowed, the number of beats per minute being actually reduced, under considerable doses, to forty, or even thirty, per minute. Interestingly, the wolfsbane flower was used to identify supposed werewolves. If the flower cast a yellow shadow on the suspected shape-shifter's chin, the werewolf test was positive.

7 Digitalis
Depending on the species, the digitalis plant may contain several deadly physiological and chemically related cardiac and steroidal glycosides. Thus, the digitalis has earned several more sinister monikers: Dead Man's Bells, and Witches' Gloves. The entire plant is toxic (including the roots and seeds), although the leaves of the upper stem are particularly potent, with just a nibble being enough to potentially cause death. Medicines from foxgloves are called "Digitalin". It is used to increase cardiac contractility (it is a positive inotrope) and as an antiarrhythmic agent to control the heart rate, particularly in the irregular (and often fast) atrial fibrillation. It is therefore often prescribed for patients in atrial fibrillation, especially if they have been diagnosed with heart failure.

6 Copperhead Venom
The copperhead is an ambush predator: it takes up a promising position and waits for suitable prey to arrive. Like most North American viperids, these snakes prefer to avoid humans and, given the opportunity, will leave the area without biting. However, unlike other viperids they will often "freeze" instead of slithering away, and as a result many bites occur from people unknowingly stepping on or near them. Copperhead venom has an estimated lethal dose of around 100 mg, and tests on mice show its potency is among the lowest of all pit vipers, and slightly weaker than that of its close relative, the cottonmouth. Copperheads often employ a "warning bite" when stepped on or agitated and inject a relatively small amount of venom, if any at all. The venom of the Southern copperhead has been found to hold a protein called "Contortrostatin" that halts the growth of cancer cells and also stops the migration of the tumors to other sites. It will probably be ten or more years before contortrostatin is used in practical treatment but it has shown to be a novel anti-cancer drug in the lab.

5 Hemlock
Hemlock is one of the most widely known poisons. The most important and toxic alkaloid in hemlock is coniine, which has a chemical structure similar to nicotine. Coniine is a neurotoxin, which disrupts the workings of the central nervous system and is toxic to humans and all classes of livestock. Coniine causes death by blocking the neuromuscular junction in a manner similar to curare; this results in an ascending muscular paralysis with eventual paralysis of the respiratory muscles which results in death due to lack of oxygen to the heart and brain. Death can easily be prevented by artificial ventilation until the effects have worn off 48-72 hours later. Ingestion of Poison Hemlock in any quantity can result in respiratory collapse and death. For an adult the ingestion of more than 100 mg of coniine (approximately 6 to 8 fresh leaves, or a smaller dose of the seeds or root) may result in fatality. Despite its deadly reputation, poison hemlock has been used as a sedative and for its antispasmodic properties. It was also used by Greek and Persian physicians for a variety of problems, such as arthritis.

4 Deadly Nightshade

Atropine is a tropane alkaloid extracted from deadly nightshade, jimsonweed (Datura stramonium), mandrake and other plants of the family Solanaceae. Injections of atropine are used in the treatment of bradycardia (an extremely low heart rate), asystole and pulseless electrical activity (PEA) in cardiac arrest. Atropine's actions on the parasympathetic nervous system inhibits salivary, sweat, and mucus glands. This can be useful in treating hyperhidrosis, and can prevent the death rattle of dying patients. Because of its extremely important use in medicine, this poison is a core medicine in the World Health Organization's "Essential Drugs List", which is a list of minimum medical needs for a basic health care system.

3 Yellow Scorpion Venom
The venom from another menacing arachnid is being used to help treat cancer. Researchers at the Transmolecular Corporation in Cambridge, Mass., have isolated a protein that occurs in the venom of the Israeli yellow scorpion. This protein has been shown to seek out and bind itself to the types of cancerous cells found in gliomas, a type of brain cancer that's particularly difficult to treat. The researchers created a synthetic version of the protein and attached radioactive iodine solution to it. When introduced into the bloodstream, the protein seeks out glioma cells and binds to them, carrying the radioactive solution along for the ride. The solution then destroys the cells - and with enough treatments, the cancer.

2 Chilean Rose Tarantula Venom
Biophysicists from the University at Buffalo are using a protein from the venom of the Chilean Rose tarantula to combat death from heart attacks. The walls of your cells have tiny channels that open when the cell stretches. Among other body functions, these channels are responsible for the contraction of heart muscles. When these channels open too wide (which can happen from stretching the heart muscles over time), they allow a flood of positive ions into the cell. These extra ions disrupt the electrical signals in the heart, causing the organ to fibrillate (beat wildly and irregularly). The protein from the Chilean tarantula venom binds to these channels, which can block the positive ions from passing through. This could ostensibly prevent fibrillation - and hopefully death - if delivered during a heart attack.

1 Ergot

Man has a long history with ergot - a fungus which infects rye (which is then transferrEd to humans who eat the grain). Ergotism causes hallucinations and attendant irrational behavior, convulsions, and even death. Other symptoms include strong uterine contractions, nausea, seizures, and unconsciousness. Consumption can lead to amputation of limbs which are damaged by the fungus. Since the middle ages, controlled doses of ergot were used to induce abortions and to stop maternal bleeding after childbirth. Ergot alkaloids are used in products such as Cafergot (containing caffeine and ergotamine or ergoline) to treat migraine headaches. It is also used in a variety of treatments for Parkinson's disease. Ergotism has even been blamed (though it is not likely the true cause) for the extremely bizarre dancing plague which struck Europe in the 1500s.

10 Insulting Words You Should Know

There is a crisis of insults on the Web. On one hand, the volume of flames is very high yet the quality is poor. Gone are the days of the razor-sharp wit of Oscar Wilde and Winston Churchill*, only to be replaced by a string of four letter words typed in ALL CAPS by n00bs (the latest of which is "FAIL", itself a failure of coming up with a more scathing insult, if you think about it).

*For example:

"Some cause happiness wherever they go; others, whenever they go," says Oscar Wilde.

George Bernard Shaw wrote to Winston Churchill, "I am enclosing two tickets to the first night of my new play; bring a friend....if you have one." And Churchill wrote back, "Cannot possibly attend first night, will attend second......if there is one"

Well, it's hard to teach wit - but all of us can learn the next best thing: the approximation of it by obfuscation, i.e. using big, difficult, and obscure words. So, to do our part in improving the quality of insults on teh Interweb, Neatorama has come up with a list of 10 Insulting Words You Should Know:

FRENCHIFY (v)

Definition: 1) To make French in quality or trait 2) To make somewhat effeminate, and 3) To contract a veneral disease (a 19th century slang).

Analysis: We have the English to thank for this word. Most people implicitly understand that it means to become more like the French, but not a lot know the second or the third meaning. We're still not sure which is more insulting.

BESCUMBER (v)

Definition: To spray with poo.

Analysis: Actually bescumber is just one of many words in the English language that basically mean "to spray with poo". These are: BEDUNG, BERAY, IMMERD, SHARNY, and the good ol' SHITTEN. In special cases, you can use BEMUTE (specifically means to drop poo on someone from great height), SHARD-BORN (born in dung), and FIMICOLOUS (living and growing on crap).

Alternative: If that is too vulgar, you can use BEVOMIT and BEPISS, which meanings should be obvious to you, as well as BESPAWL (to spit on).

Oh, and if you want to say poo without looking like you're saying it, you can use ORDURE, DEJECTION, and EXCRETA. To mean something more specific, you can use MECONIUM (first feces of a newborn child), MELAENA or MELENA (the abnormally tarry feces containing blood from gastrointestinal bleeding), LIENTERY (diarrhea with undigested or partially digested food), and STEATORRHEA (fatty stool that's hard to flush down).

Here are some words along the same line that may one day prove to be useful for you: TURDIFY (turn into turd), COPROPHAGIA (eating of feces [wiki]), and COPROPHILIA (Think 2 Girls 1 Cup [wiki - don't worry, SWF], if you don't know what this is, I shan't corrupt you any further).

Let's end entry number two with these two amazing words COPREMESIS and MISERERE, both of which mean fecal vomiting. Yes, fecal vomiting. It's a medical emergency caused by the obstruction of the bowel (source).


MICROPHALLUS (n)

Definition: An unusually small penis.

Analysis: Self explanatory.

Alternative: Insulting a man's private part is a very reliable way to put him down (if he's smaller than you) or to get beat up (if he's larger than you). Usually, even a dimwit can decipher the meaning of this word, after all, it's just a combination of "micro" and "phallus".

So, to insult a physically larger opponent, we recommend you use these words instead: PHALLOCRYPSIS (retraction or shrinkage of the penis), CRYPTORCHID (undescendend testicles), and PHALLONCUS (tumor of the penis).


COCCYDYNIA (n)

Definition: Pain in the butt.

Analysis: It's a real medical term: coccydynia is pain in the coccyx or tailbone. Most people simply call it "buttache."

Similar: PROCTALGIA, PROCTODYNIA, PYGALGIA and RECTALGIA all mean pain in the butt.

Alternative: CERVICALGIA (pain in the neck), PHALLODYNIA or PHALLALGIA (both mean pain in the penis), and PUDENDAGRA (pain in the genitals).

The word "butt" is highly versatile in its vernacular use - you can say "butt face" or "hairy butt" - dem are fightin' words - but it's much better to use these instead: ANKYLOPROCTIA (stricture of the anus, the state of "tight-assity"), STEATOPYGOUS (fat-assed), DASYPYGAL (having hairy buttocks), and CACOPYGIAN (having ugly buttocks).




NINNYHAMMER (n)

Definition: A fool or a silly person.
Analysis: The word "fool," unless you're Mr. T, is sometimes woefully inadequate to express the stupidity of the person you're talking about. So use Ninnyhammer. Or at least NINNY.

Alternative: The English language is chockful of colorful words meaning stupid person, such as: DUMMKOPF, IGNORAMUS, JOBBERNOWL, GOWK, and WITLING.

For mental retardation, eschew the ubiquitous 'tard - rather, use AMENTIA (extreme mental retardation because of inadequate brain tissue), CRETINISM (mental retardation associated with dwarfism, caused by the deficiency of a thyroid hormone, a person with cretinism is a CRETIN), and MORONITY (used to mean mild retardation of having a mental age of 7 to 12 years, now it's an obsolete term though we still use the word moron).


BUNCOMBE (n)

Definition: A ludicrously false statement. Basically it means bullshit or nonsense.

Analysis: Actually, you probably already know this word by its more common spelling: bunkum.

The origin of this word is fascinating. In 1819, a North Carolina congressman, the Honorable Felix Walker, was giving a rambling speech with little relevance to the current debate. He refused to yield the floor, and claimed that he wasn't speaking for Congress but instead "for Buncombe" (a county in North Carolina he represented). That's all it took.

Over time, the spelling changed to "bunkum," and the meaning strangely changed to be "excellent." Then it changed back in 1870, when a San Francisco gambler introduced a new game "banco" played with dice that were later found out to be loaded. Sure enough, BUNCO became known to mean swindle or cheat, and bunkum reverted back to its original meaning. (Source)

The word DEBUNK came directly from this: it's just bunk(um) with the prefix de- (meaning to remove).


HIRCISMUS (n)

Definition: Offensive armpit odor.

Analysis: Hircismus comes from the root word "hircus" which means goat in Latin. Someone must have thought smelly pits smelled like goats. Actually, this word combines two sources of great insult potential: smelly and armpits. Why this is not used more often in the discourse of hateful communication is beyond me.

Alternative: As we've mentioned, armpit is an untapped goldmine for insults. Here are some examples of words you can use: MASCHALEPHIDROSIS or MASCHALYPERIDROSIS (excessive sweating of the armpits). MASCHALOPHILOUS (sexual attraction to the underarms) and AXILLISM (the use of armpit for sex).

Smelling like goats is also a good source of insults (especially since goat is also a slang for a lecherous man). Try CAPRYLIC and HIRCINE (smelling like a pungent goat), and CAPRIC (resembling a goat).


CORPULENT (adj)

Definition: Very fat.

Analysis: Good ol' fat is a reliable insult word. After all, nowadays, no one like a fatty ... except Mauritanian men. That's right: in the Islamic Republic of Mauritania, fat and Rubenesque women are sexy and desirable. So much so, that instead of the crash diet of the West, they have a similar but opposite program: crash feeding or "gavage," where girls as young as 5 years old are force-fed milk, cream, butter, couscous and other calorie-rich food:

Girls as young as 5 and as old as 19 had to drink up to five gallons of fat-rich camel's or cow's milk daily, aiming for silvery stretch marks on their upper arms. If a girl refused or vomited, the village weight-gain specialist might squeeze her foot between sticks, pull her ear, pinch her inner thigh, bend her finger backward or force her to drink her own vomit. In extreme cases, girls died. (Source)

Interestingly, the ideal man is skinny (Mauritanians view portly men as womanish and lazy).

Alternative: ABDOMINOUS (potbellied), STEATOPYGOUS (fat-assed), and FUSSOCK (a very fat woman).


FEIST or FICE (n)

Definition: 1) A small dog of uncertain ancestry, a mongrel. 2) A person of little worth or someone with a bad temper, and 3) Silent fart.

Analysis: You actually already know this word: feist is used throughout the Midland and Southern United States to mean a snappy, nervous and belligerent little dog. The adjective feisty which means "full of spirit or spunky," comes from this word. But that's not why it's on this list (hint: #3!)

What you may not know is the true origin of the word. Feist comes from the Middle English fisten, which means to break wind (fist originally also meant flatus or fart). Feist is a special type of fart: the silent (and often deadly) type. Oh, and the word "fart" itself comes from another Middle English word farten or ferten, which in turn is from the Old English feortan.

Feist is the type of word that, if introduced to young adolescents, no doubt would spark a lifelong interest in learning new words.

Alternative: Fart is another one of those goldmines of insults. To obfuscate what you really mean, use instead: FLATUOSITY (fart). Other gems: EPROCTOLAGNIAC (someone aroused by flatulence, his own or someone else's), CARMINATIVE (something that makes you fart), and BDOLOTIC (prone to farting).


CACAFUEGO (n)

Definition: A swaggering braggart or boaster.

Analysis: Cacafuego literally means "shit fire" in Spanish. Anyone who boasts their new knowledge of insulting words from this article can be called a cacafuego.

That's not the only interesting thing about it:

Cacafuego is also the nickname of a 16th century Spanish galleon captured by Sir Francis Drake (El Draque or The Dragon as he was known to his Spanish victims). The ship's original name was Nuestra Señora de la Concepción (Our Lady of Conception), but for some reason it's called by her sailors as "cagafuego" (fireshitter) or "cacafuego" (shitfire).

It was Drake's biggest plunder: it took his crew four days to transfer the cargo from the Cacafuego. In all, Drake got 80 pounds of gold, 26 tons of silver, 13 cases of silver coins, jewels, and more.

Synonym: BLATHERSKITE, BRAGGADOCIO, FANFARON, GASCONADER, and RODOMONTADE (English is full of this kind of word, though I think caca "shit fire" fuego is in a class of its own!)

Brabus Mercedes-Benz S600 iBusiness

Next: World's tallest building - Nakheel Tower more than 1 km in Dubai

Skyscraper Burj Dubai is only dostraivaetsya, but already there are projects that can take away from the sensational tower in Dubai title of the highest buildings. Australian architect Woods Begot (Woods Bagot) has drafted a skyscraper for the company Nakheel, which on the coast of Dubai will build a tower height of more than 1 kilometer.
200-storey tower Nakheel Tower will be built by 2020.